Linezolid use in hospitalized children

Pediatr Infect Dis J. 2014 Jan;33(1):e14-8. doi: 10.1097/INF.0000000000000011.

Abstract

We used the Pediatric Health Information System to evaluate linezolid use among hospitalized children. From 2003 to 2007, use increased 5-fold, including wide interhospital variation, then stabilized through 2011. Linezolid was responsible for 3% of total antibiotic expenditures. Children with respiratory, oncologic or transplant conditions were the most frequently treated with linezolid.

MeSH terms

  • Acetamides / administration & dosage*
  • Adolescent
  • Anti-Bacterial Agents / administration & dosage*
  • Child
  • Child, Preschool
  • Drug Prescriptions / statistics & numerical data*
  • Female
  • Hospitalization / statistics & numerical data*
  • Humans
  • Infant
  • Linezolid
  • Male
  • Methicillin-Resistant Staphylococcus aureus
  • Oxazolidinones / administration & dosage*
  • Staphylococcal Infections / drug therapy

Substances

  • Acetamides
  • Anti-Bacterial Agents
  • Oxazolidinones
  • Linezolid