[New clone of ST-187 Acinetobacter baumannii responsible for an outbreak in an intensive care unit]

Enferm Infecc Microbiol Clin. 2014 Apr;32(4):242-5. doi: 10.1016/j.eimc.2013.10.014. Epub 2013 Dec 21.
[Article in Spanish]

Abstract

Introduction: An ICU-outbreak caused by a novel Acinetobacter baumannii clone is described.

Methods: An active search of carriers and environmental reservoirs was carried out. Carbapenemases genes were studied using multiplex-PCR and genotypic analysis by rep-PCR, PFGE and MLST.

Results: A total 26 infected patients and 10 carriers were identified. A.baumannii was recovered from infusion pumps, walls, floor and washbasins. Phenotypic/genotypic analysis showed clonal expansion of a unique clone ST-187 producer of type OXA-24 and OXA-51 carbapenemases.

Discussion: This is the first outbreak caused by ST-187 (ECI/GCI) multiresistant A.baumannii.

Keywords: Acinetobacter baumannii; MLST; Multiresistance; Multirresistencia.

MeSH terms

  • Acinetobacter Infections / epidemiology*
  • Acinetobacter baumannii / drug effects
  • Acinetobacter baumannii / genetics*
  • Bacterial Proteins / genetics
  • Disease Outbreaks*
  • Drug Resistance, Multiple, Bacterial
  • Female
  • Humans
  • Intensive Care Units
  • Male
  • Middle Aged
  • Retrospective Studies
  • beta-Lactamases / genetics

Substances

  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase