Bone marrow monocyte-/macrophage-derived activin A mediates the osteoclastogenic effect of IL-3 in multiple myeloma

Leukemia. 2014 Apr;28(4):951-4. doi: 10.1038/leu.2013.385. Epub 2013 Dec 26.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Activins / physiology*
  • Animals
  • Bone Diseases / etiology*
  • Humans
  • Interleukin-3 / pharmacology*
  • Macrophages / physiology*
  • Mice
  • Mice, Inbred C57BL
  • Monocytes / physiology*
  • Multiple Myeloma / complications*
  • Osteoclasts / drug effects
  • Osteoclasts / physiology*
  • Osteogenesis / drug effects*
  • RANK Ligand / physiology

Substances

  • Interleukin-3
  • RANK Ligand
  • activin A
  • Activins