Topical treatment of recurrent vaginal melanoma in situ with imiquimod: A case report

Lauren S Prescott; Nicholas E Papadopoulos; Elizabeth D Euscher; Jack L Watkins; Kathleen M Schmeler

doi:10.1016/j.gynor.2012.04.004

Topical treatment of recurrent vaginal melanoma in situ with imiquimod: A case report

Gynecol Oncol Case Rep. 2012 Apr 30;2(3):92-3. doi: 10.1016/j.gynor.2012.04.004. eCollection 2012.

Authors

Lauren S Prescott¹, Nicholas E Papadopoulos², Elizabeth D Euscher³, Jack L Watkins⁴, Kathleen M Schmeler⁵

Affiliations

¹ Department of Obstetrics and Gynecology, Dartmouth-Hitchcock Medical Center, NH, USA.
² Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, TX, USA.
³ Department of Pathology, The University of Texas MD Anderson Cancer Center, TX, USA.
⁴ Department of Pharmacy, The University of Texas MD Anderson Cancer Center, TX, USA.
⁵ Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, TX, USA.

Abstract

► Vaginal melanoma in situ is a rare neoplasm with a paucity of data regarding the optimal management. ► More conservative approaches are needed to avoid the disfigurement, pain and postoperative complications associated with repeated surgical interventions. ► Imiquimod may prove to be a useful treatment modality for patients with vulvar or vaginal melanoma in situ.

Keywords: Imiquimod; Melanoma; Melanoma-in-situ; Vaginal neoplasm; Vulvar neoplasm.