High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor

Affiliations

• ¹ Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA; Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA; Case Comprehensive Cancer Center, Cleveland, OH 44106, USA. Electronic address: [email protected].
• ² Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA; Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA; Laboratory of Biochemistry and Molecular Biology, School of Life Sciences, Yunnan University, Kunming 650091, China.
• ³ Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA.
• ⁴ Department of Cellular and Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA.
• ⁵ Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA.
• ⁶ Department of Pathology, Odense University Hospital, Institute of Clinical Research, University of Southern Denmark, Odense 5000, Denmark.
• ⁷ Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA.
• ⁸ BD Biosciences, La Jolla, CA 92037, USA.
• ⁹ Department of Neurological Surgery, James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
• ¹⁰ Department of Oncology, Odense University Hospital, Institute of Clinical Research, University of Southern Denmark, Odense 5000, Denmark.
• ¹¹ Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.
• ¹² Case Comprehensive Cancer Center, Cleveland, OH 44106, USA; Seidman Cancer Center, University Hospital-Case Medical Center, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA; Departments of Neurological Surgery, Pathology, and Translational Neuroscience, University Hospital-Case Medical Center, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.
• ¹³ Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA; Case Comprehensive Cancer Center, Cleveland, OH 44106, USA.
• ¹⁴ Department of Biology, University of Delaware, Newark, DE 19716, USA.
• ¹⁵ Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195, USA; Case Comprehensive Cancer Center, Cleveland, OH 44106, USA. Electronic address: [email protected].