Long-term evaluation of patients undergoing genitoplasty due to disorders of sex development: results from a 14-year follow-up

ScientificWorldJournal. 2013 Nov 25:2013:298015. doi: 10.1155/2013/298015. eCollection 2013.

Abstract

Purpose: To summarize the experience in treating patients with genitoplasty due to disorders of sex development in China.

Methods: The operative procedures, gender of rearing, surgical outcome, and psychosocial and family adjustments of 262 patients were reviewed retrospectively.

Results: At initial diagnosis, the mean age was 14.3 ± 2.8 years (range: 2-38 years). There were 96 children, 133 adolescents, and 33 adults. Follow-up was done every 6 months. Patients with female sex assignment had no urinary incontinence or voiding difficulty. Five patients underwent the second surgery (3%); vaginal dilation was performed in 35 patients with postoperative vaginal stenosis; 12 patients (7.4%) were unsatisfactory with the outcome. For patients with male sex assignment, the median length of penis was 2.2 cm in prepubertal patients, 4.2 cm in pubertal patients, and 5.0 cm in adults; 39 patients developed postvoid dribbling (39%); 21 patients underwent a second surgery (21%); urethral dilation was done in 28 patients (28%) due to urethral stricture; 38 patients were unsatisfactory with the outcome (38%). In addition, 136 patients (83%) with female sex assignment and 54 (54%) with male sex assignment had favorable psychosocial adjustment.

Conclusions: Patients with male sex assignment have more surgical complications and difficulties in psychosocial adjustment as compared to those with female sex assignment.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Disorders of Sex Development / epidemiology
  • Disorders of Sex Development / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Sex Characteristics*
  • Sex Reassignment Procedures / adverse effects*