Molecular typing of monophasic Salmonella 4,[5]:i:- strains isolated in Belgium (2008-2011)

Vet Microbiol. 2014 Jan 31;168(2-4):447-50. doi: 10.1016/j.vetmic.2013.11.040. Epub 2013 Dec 14.

Abstract

To assess the distribution of Salmonella 4,[5]:i:- subtypes in the Belgian food chain and compare it to the subtypes associated with human infections, a molecular assessment was initiated. Two hundred fifty-three Salmonella isolates serotyped as 4,[5]:i:- during the period 2008-2011 in Belgium and originating from animal productions, food or human clinical samples were analysed by a specific duplex PCR. One hundred ninety-four isolates (76.7%) fit the profile of a S. Typhimurium monophasic variant as defined by the European Food Safety Authority. The other isolates possessed but did not express the phase II flagellin gene (23.3%). Multiple Locus Variable Number of Tandem Repeats Analysis (MLVA) revealed many but closely related profiles in the fljB-negative S. Typhimurium monophasic variant isolates. Some MLVA types were associated with both human and animal isolates but no unique source of human contamination could be demonstrated.

Keywords: 4,[5]:i:-; MLVA; Monophasic; Salmonella; Typhimurium.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacteriophage Typing
  • Belgium
  • Flagellin / genetics
  • Food Safety / methods*
  • Humans
  • Molecular Typing
  • Polymerase Chain Reaction
  • Salmonella / genetics
  • Salmonella Food Poisoning / epidemiology
  • Salmonella Food Poisoning / microbiology*
  • Salmonella Food Poisoning / prevention & control
  • Salmonella Infections / epidemiology
  • Salmonella Infections / microbiology*
  • Salmonella Infections / prevention & control
  • Salmonella typhimurium / classification
  • Salmonella typhimurium / genetics*
  • Salmonella typhimurium / isolation & purification*
  • Tandem Repeat Sequences

Substances

  • Flagellin