Digital response in T cells: to be or not to be

Felix Wertek; Chenqi Xu

doi:10.1038/cr.2014.5

Digital response in T cells: to be or not to be

Cell Res. 2014 Mar;24(3):265-6. doi: 10.1038/cr.2014.5. Epub 2014 Jan 10.

Authors

Felix Wertek¹, Chenqi Xu²

Affiliations

¹ 1] National Center for Protein Science Shanghai, State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China [2] University of Heidelberg, Institute of Pharmacy and Molecular Biotechnology, 69120 Heidelberg, Germany.
² National Center for Protein Science Shanghai, State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

Abstract

A recent study published in Immunity shows that foreign antigens elicit all-or-nothing T cell responses and that a single antigen is enough to trigger this digital cytokine secretion.

Publication types

Comment

MeSH terms

Animals
CD4-Positive T-Lymphocytes / metabolism*
Histocompatibility Antigens Class II / immunology*
T-Lymphocyte Subsets / metabolism*

Substances

Histocompatibility Antigens Class II