Abstract
We evaluated vancomycin minimum inhibitory concentration (MIC) trends by 3 methods (broth microdilution, Etest and Vitek 2) in 208 Staphylococcus aureus blood isolates from 2006 to 2009 and assessed for heteroresistance. Vancomycin MICs did not increase nor was heteroresistance identified. Etest yielded higher MIC results than the other 2 methods. No MIC was >2 µg/mL by any testing method.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Bacteremia / microbiology
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Child
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Humans
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Methicillin-Resistant Staphylococcus aureus / drug effects
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Microbial Sensitivity Tests
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Retrospective Studies
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Staphylococcal Infections / blood
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Staphylococcal Infections / microbiology*
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Staphylococcus aureus / drug effects*
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Staphylococcus aureus / isolation & purification
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Vancomycin / pharmacology*
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Vancomycin Resistance*
Substances
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Anti-Bacterial Agents
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Vancomycin