[Medium-term acceptability of HIV vaccine clinical trials in Burkina Faso: stakeholders' perceptions]

Sante Publique. 2013 Sep-Oct;25(5):675-83.
[Article in French]

Abstract

Introduction: The ideal response to HIV would be the discovery of an effective vaccine. Evaluation of the benefit/risk balance of this vaccine must include Africa, where the majority of HIV infections are observed. This study was designed to identify the perceptions and the medium-term acceptability of a potential vaccine trial in Ouagadougou (Burkina Faso).

Methods: After a "literature review", data were collected from key informants, "pimps" of prostitutes, representatives of HIV and/or AIDS associations, facilitators and peer educators. Data were transcribed and analysed manually.

Results: The vast majority of respondents considered that it would be relevant to test an HIV vaccine in Ouagadougou (Burkina Faso). Almost all prostitutes would participate in such a trial and would be motivated by several factors. Potential participants were willing to play the role expected of them. A real communication strategy will be needed to conduct this trial.

Discussion: The results of this study are similar to those of previous studies conducted in Burkina Faso concerning the acceptability/feasibility of clinical trials. Acceptability studies of clinical trials are therefore becoming less and less relevant. Reinforcing the skills/capacities of all stakeholders and/or adequate preparation of participants to play the role expected of them are therefore now more important than acceptability studies.

Publication types

  • English Abstract

MeSH terms

  • AIDS Vaccines*
  • Adult
  • Attitude to Health*
  • Burkina Faso
  • Clinical Trials as Topic
  • Female
  • Humans
  • Male
  • Research Subjects*
  • Sex Workers

Substances

  • AIDS Vaccines