Hydrocortisone directly promotes cholesterol accumulation in macrophages

Ann Rheum Dis. 2014 Jun;73(6):1274-6. doi: 10.1136/annrheumdis-2013-204806. Epub 2014 Jan 15.
No abstract available

Keywords: Atherosclerosis; Autoimmune Diseases; Corticosteroids; Lipids.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Inflammatory Agents / adverse effects
  • Anti-Inflammatory Agents / pharmacology*
  • Atherosclerosis / chemically induced
  • Atherosclerosis / metabolism
  • Cell Line, Tumor
  • Cholesterol / metabolism
  • Cholesterol, LDL / metabolism*
  • Foam Cells / drug effects
  • Foam Cells / metabolism
  • Humans
  • Hydrocortisone / adverse effects
  • Hydrocortisone / pharmacology*
  • Macrophages / drug effects*
  • Macrophages / metabolism

Substances

  • Anti-Inflammatory Agents
  • Cholesterol, LDL
  • Cholesterol
  • Hydrocortisone