Pulmonary cavitation and skin lesions mimicking tuberculosis in a HIV negative patient caused by Sporothrix brasiliensis

Rosane Orofino-Costa; Natasha Unterstell; Alexandre Carlos Gripp; Priscila Marques de Macedo; Arles Brota; Emylli Dias; Marcus de Melo Teixeira; Maria Sueli Felipe; Andréa R Bernardes-Engemann; Leila Maria Lopes-Bezerra

doi:10.1016/j.mmcr.2013.02.004

Pulmonary cavitation and skin lesions mimicking tuberculosis in a HIV negative patient caused by Sporothrix brasiliensis

Med Mycol Case Rep. 2013 Feb 16:2:65-71. doi: 10.1016/j.mmcr.2013.02.004.

Affiliations

¹ Dermatology Department, Universidade do Estado do Rio de Janeiro, Av. 28 de Setembro 87, Rio de Janeiro 20551-030, Brazil.
² Laboratory of Cellular Mycolgy and Proteomics, Universidade do Estado do Rio de Janeiro, Rua São Francisco Xavier, 524 PHLC sl 501D, Rio de Janeiro 20550-013, Brazil.
³ Department of Cell Biology, Universidade de Brasília, Brasília DF 70910-900, Brazil.

Abstract

A 32-year-old HIV negative male presented with multiple pulmonary cavitation and skin abscesses up to 15 cm in diameter mimicking tuberculosis. Sporothrix brasiliensis was isolated and patient responded well to amphotericin B followed by itraconazole, except the skin lesions that had to be surgical drained to obtain cure.

Keywords: Amphotericin B; Genotyping; Pulmonary sporotrichosis; Serology; Sporothrix brasiliensis.