European Medicines Agency initiatives and perspectives on pharmacogenomics

Br J Clin Pharmacol. 2014 Apr;77(4):612-7. doi: 10.1111/bcp.12319.

Abstract

Pharmacogenomics, the study of variations of DNA and RNA characteristics as related to drug response, has become an integral part of drug development and pharmacovigilance, as reflected by the incorporation of pharmacogenomic data in EU product information. In this short review article, we describe recent European Medicines Agency initiatives intended to support further the implementation of pharmacogenomics in drug development and surveillance so that patients and the public can benefit from advances in genomic science and technology.

Keywords: European Medicines Agency; guidance; pharmacoepigenetics; pharmacogenomics; regulator.

Publication types

  • Review

MeSH terms

  • Drug Discovery / trends*
  • Europe
  • Guidelines as Topic
  • Humans
  • Pharmacogenetics / trends*
  • Pharmacovigilance