[Use of misoprostol in gynaecology]

J Gynecol Obstet Biol Reprod (Paris). 2014 Feb;43(2):190-4. doi: 10.1016/j.jgyn.2013.11.013. Epub 2014 Jan 13.
[Article in French]

Abstract

Objectives: To assess the interest of misoprostol in gynaecology and particularly for cervical priming.

Method: Research in PubMed in English and French about misoprostol and its use in gynaecology.

Results: We summarized the results of 3 meta-analyses, randomized controlled trials and literature review. Results show that misoprostol did not scientifically prove a benefit for cervical priming before hysteroscopy or before intra-uterine device (IUD). Results are the same with post-menopausal or nulliparous women. It did not lead either to lower the complications but increase adverse effects.

Conclusion: It is not indicated to use misoprostol for cervical priming in gynaecology.

Keywords: Cervical priming; DIU; Dilatation cervicale; Hysteroscopy; Hystéroscopie; IUD; Misoprostol.

Publication types

  • English Abstract
  • Meta-Analysis
  • Review

MeSH terms

  • Cervical Ripening
  • Cervix Uteri / drug effects*
  • Female
  • Gynecology / methods*
  • Humans
  • Hysteroscopy / methods
  • Intrauterine Device Expulsion
  • Misoprostol / adverse effects
  • Misoprostol / therapeutic use*
  • Parity
  • Postmenopause
  • Pregnancy
  • Randomized Controlled Trials as Topic

Substances

  • Misoprostol