Feasibility study on pinhole camera system for online dosimetry in boron neutron capture therapy

Tatsuya Katabuchi; Brian Hales; Noriyosu Hayashizaki; Masayuki Igashira; Zareen Khan; Tooru Kobayashi; Taihei Matsuhashi; Koichi Miyazaki; Koichi Ogawa; Kazushi Terada

doi:10.1016/j.apradiso.2013.12.026

Feasibility study on pinhole camera system for online dosimetry in boron neutron capture therapy

Appl Radiat Isot. 2014 Jun:88:139-42. doi: 10.1016/j.apradiso.2013.12.026. Epub 2013 Dec 31.

Affiliations

¹ Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550, Japan. Electronic address: [email protected].
² Research Laboratory for Nuclear Reactors, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550, Japan.
³ Research Reactor Institute, Kyoto University, Kumatori-cho, Sennan-gun, Osaka 590-0494, Japan.
⁴ Department of Applied Informatics, Faculty of Science and Engineering, Hosei University, 3-7-2 Kajino-cho, Koganei, Tokyo 184-8584, Japan.

PMID: 24433991
DOI: 10.1016/j.apradiso.2013.12.026

Abstract

The feasibility of a pinhole camera system for online dosimetry in boron neutron capture therapy (BNCT) was studied. A prototype system was designed and built. Prompt γ-rays from the (10)B(n,α)(7)Li reaction from a phantom irradiated with neutrons were detected with the prototype system. An image was reconstructed from the experimental data. The reconstructed image showed a good separation of the two borated regions in the phantom. The counting rates and signal-to-noise ratio when using the system in actual BNCT applications are also discussed.

Keywords: Boron neutron capture therapy; CdTe detector; Online dosimetry; Pinhole camera.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Boron Neutron Capture Therapy / instrumentation*
Equipment Design
Equipment Failure Analysis
Feasibility Studies
Gamma Cameras*
Online Systems
Radiometry / instrumentation*
Reproducibility of Results
Sensitivity and Specificity
Tomography, Emission-Computed, Single-Photon / instrumentation*