Background: The aim of our study was to identify potential risk factors for anal fistula in order to improve prevention and treatment of anal fistula.
Methods: A retrospective case-control study for anal fistula was conducted at our unit. Logistic regression analyses were carried out to identify associated risk factors for anal fistula.
Results: The final model obtained by the stepwise forward logistic regression analysis method identified the following items as independent risk factors: body mass index of >25.0 kg/m(2), high daily salt intake, history of diabetes, hyperlipidemia, dermatosis, anorectal surgery, history of smoking and alcohol intake, sedentary lifestyle, excessive intake of spicy/greasy food, very infrequent participation in sports and prolonged sitting on the toilet for defecation.
Conclusions: Our results indicate that lifestyle factors and certain medical conditions increase an individual's risk of developing anal fistula.