Nrf-2-HO-1-HMGB1 axis: an important therapeutic approach for protection against myocardial ischemia and reperfusion injury

Int J Cardiol. 2014 Mar 1;172(1):223-4. doi: 10.1016/j.ijcard.2013.12.273. Epub 2014 Jan 11.

Authors

Jichun Wang¹, Xiaorong Hu¹, H Jiang²

Affiliations

¹ Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute of Wuhan University, Jiefang Road 238, Wuchang, 430060 Wuhan, PR China.
² Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute of Wuhan University, Jiefang Road 238, Wuchang, 430060 Wuhan, PR China. Electronic address: [email protected].

PMID: 24456890
DOI: 10.1016/j.ijcard.2013.12.273

No abstract available

Keywords: Cardioprotection; Heme oxygenase-1; Myocardial ischemia and reperfusion; Nrf-2; Oxidative stress.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

HMGB1 Protein / metabolism*
Heme Oxygenase-1 / metabolism*
Humans
Myocardial Reperfusion Injury / genetics
Myocardial Reperfusion Injury / metabolism*
NF-E2-Related Factor 2 / genetics*
NF-E2-Related Factor 2 / metabolism*
Oxidative Stress / physiology*

Substances

HMGB1 Protein
HMGB1 protein, human
NF-E2-Related Factor 2
NFE2L2 protein, human
HMOX1 protein, human
Heme Oxygenase-1