TNFRII polymorphism is associated with response to TNF blockers in rheumatoid arthritis patients seronegative for ACPA

Joint Bone Spine. 2014 Jul;81(4):370-2. doi: 10.1016/j.jbspin.2013.12.005. Epub 2014 Jan 22.
No abstract available

Keywords: Anti-citrullinated peptide antibodies (ACPA); Biomarkers; Genetic polymorphism; SNP IL10-1087; SNP LTA+720; SNP TNFRII-codon 196; TNF response.

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antirheumatic Agents / therapeutic use*
  • Arthritis, Rheumatoid / drug therapy*
  • Arthritis, Rheumatoid / genetics*
  • Arthritis, Rheumatoid / immunology
  • Humans
  • Male
  • Middle Aged
  • Peptides, Cyclic / immunology
  • Polymorphism, Genetic
  • Predictive Value of Tests
  • Receptors, Tumor Necrosis Factor, Type II / genetics*
  • Receptors, Tumor Necrosis Factor, Type II / immunology
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors*
  • Young Adult

Substances

  • Antirheumatic Agents
  • Peptides, Cyclic
  • Receptors, Tumor Necrosis Factor, Type II
  • Tumor Necrosis Factor-alpha
  • cyclic citrullinated peptide