Microfocus X-ray imaging of the internal geometry of brachytherapy seeds

Tomoyuki Hasegawa; Takashi Hanada; Atsunori Yorozu; Hidetaka Ito; Shinji Masuda; Maki Kawahara; Katsunori Yogo; Kazushige Hayakawa

doi:10.1016/j.apradiso.2013.12.032

Microfocus X-ray imaging of the internal geometry of brachytherapy seeds

Appl Radiat Isot. 2014 Apr:86:13-20. doi: 10.1016/j.apradiso.2013.12.032. Epub 2014 Jan 3.

Authors

Tomoyuki Hasegawa¹, Takashi Hanada², Atsunori Yorozu³, Hidetaka Ito⁴, Shinji Masuda⁴, Maki Kawahara⁵, Katsunori Yogo⁶, Kazushige Hayakawa⁷

Affiliations

¹ School of Allied Health Sciences, Kitasato University, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan; Graduate School of Medical Sciences, Kitasato University, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan. Electronic address: [email protected].
² Department of Radiology, Keio University, School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo 160-8582, Japan.
³ Department of Radiology, Tokyo Medical Center, National Hospital Organization, Higashigaoka 2-5-1, Meguro-ku, Tokyo 152-8902, Japan.
⁴ Kanagawa Industrial Technology Center (KITC), Shimoimaizumi 705-1, Ebina-shi, Kanagawa 243-0435, Japan.
⁵ School of Allied Health Sciences, Kitasato University, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan.
⁶ Graduate School of Medical Sciences, Kitasato University, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan.
⁷ Graduate School of Medical Sciences, Kitasato University, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan; Department of Radiology and Radiation Oncology, Kitasato University School of Medicine, Kitasato 1-15-1, Minami-ku, Sagamihara, Kanagawa 252-0374, Japan.

PMID: 24462944
DOI: 10.1016/j.apradiso.2013.12.032

Abstract

Precise and reliable geometrical data on the internal structure of seeds are indispensable for dosimetric calculation in brachytherapy. We used a novel microfocus X-ray imaging technique for observing the internal structure of brachytherapy seeds. Two popular (125)I seed models were evaluated. Obtained high precision images enabled us to observe the internal structure of seeds qualitatively. Geometrical size parameters were evaluated quantitatively with uncertainty of 0.01-0.04 mm (k=2).

Keywords: Brachytherapy; Internal geometry; Microfocus X-ray imaging; Model 6711; Model STM1251.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Brachytherapy / methods*
Diagnostic Imaging*
Humans
Radiotherapy Dosage
Tomography, X-Ray Computed
X-Rays