[Rescue treatment in acute thrombosis of intracranial stents]

Rev Neurol. 2014 Feb 1;58(3):113-6.
[Article in Spanish]

Abstract

Introduction: Acute intrastent thrombosis is a potentially serious complication in intracranial stenting. It is essential to determine which therapy is the most suitable in intrastent thromboses.

Case report: Female aged 58, the first case of acute thrombosis of an intracranial stent to be treated successfully by fibrinolysis after the implantation of a flow diverter device (Silk) in a fusiform basilar aneurysm.

Conclusion: The administration of abciximab as a rescue treatment seems safe in cases involving the formation of acute intrastent thromboses.

Title: Tratamiento de rescate en la trombosis aguda del stent intracraneal.

Introduccion. La trombosis aguda intrastent es una complicacion potencialmente grave en el stenting intracraneal. Es primordial determinar cual es la terapia mas adecuada en las trombosis intrastent. Caso clinico. Mujer de 58 años, el primer caso de trombosis aguda de un stent intracraneal, que fue tratada con exito mediante fibrinolisis tras la implantacion de un dispositivo diversificador de flujo (Silk) en un aneurisma basilar fusiforme. Conclusion. La administracion de abciximab como tratamiento de rescate parece segura en los casos de formaciones de trombos agudos intrastent.

Publication types

  • Case Reports

MeSH terms

  • Abciximab
  • Antibodies, Monoclonal / administration & dosage
  • Antibodies, Monoclonal / therapeutic use*
  • Aspirin / therapeutic use
  • Basilar Artery / surgery
  • Capillary Permeability
  • Cerebral Angiography
  • Clopidogrel
  • Equipment Design
  • Female
  • Fibrinolytic Agents / administration & dosage
  • Fibrinolytic Agents / therapeutic use*
  • Hemorheology
  • Humans
  • Immunoglobulin Fab Fragments / administration & dosage
  • Immunoglobulin Fab Fragments / therapeutic use*
  • Intracranial Aneurysm / complications
  • Intracranial Aneurysm / surgery*
  • Intracranial Thrombosis / drug therapy*
  • Intracranial Thrombosis / etiology
  • Middle Aged
  • Platelet Aggregation Inhibitors / therapeutic use
  • Recurrence
  • Salvage Therapy*
  • Stents / adverse effects*
  • Thrombolytic Therapy*
  • Ticlopidine / analogs & derivatives
  • Ticlopidine / therapeutic use

Substances

  • Antibodies, Monoclonal
  • Fibrinolytic Agents
  • Immunoglobulin Fab Fragments
  • Platelet Aggregation Inhibitors
  • Clopidogrel
  • Ticlopidine
  • Aspirin
  • Abciximab