Value of third sputum smear for detection of pulmonary tuberculosis in HIV infected patients

Majid Marjani; Payam Tabarsi; Parvaneh Baghaei; Davoud Mansouri; Mohammad Reza Masjedi; Ali Akbar Velayati

doi:10.4081/idr.2012.e35

Value of third sputum smear for detection of pulmonary tuberculosis in HIV infected patients

Infect Dis Rep. 2012 Jul 24;4(2):e35. doi: 10.4081/idr.2012.e35. eCollection 2012 Apr 27.

Authors

Majid Marjani¹, Payam Tabarsi¹, Parvaneh Baghaei¹, Davoud Mansouri¹, Mohammad Reza Masjedi¹, Ali Akbar Velayati¹

Affiliation

¹ Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Disease, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract

We evaluated diagnostic yield of third sputum smear in patients co infected with HIV for detection of pulmonary tuberculosis (TB). Among 139 pulmonary tuberculosis cases confirmed with positive sputum culture, diagnostic yield of first smear of sputum with acid fast staining was 81.9%. Incremental yield of 2(nd) and 3(rd) samples was 11.7% and 6.3% respectively. So two sputum smears may be enough for primary evaluation of HIV infected patients suspected to TB.

Keywords: HIV; diagnosis; pulmonary infection; sputum.; tuberculosis.

Publication types

Review