Abstract
We report that in a population of allogeneic stem cell transplant recipients, determination of the viral doubling time (dt) of the cytomegalovirus (CMV) DNA plasma load predicted the eventual need for inception of preemptive antiviral therapy, whereas the level of the initial plasma CMV DNA load did not. The data thus indicated that determination of the dt of CMV DNA may be useful in the therapeutic management of CMV infection in this clinical setting.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Cytomegalovirus / isolation & purification*
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Cytomegalovirus Infections / diagnosis
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Cytomegalovirus Infections / virology*
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DNA, Viral / blood*
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Female
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Humans
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Male
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Middle Aged
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Molecular Diagnostic Techniques / methods
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Plasma / virology*
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Prognosis
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Real-Time Polymerase Chain Reaction / methods
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Stem Cell Transplantation / adverse effects*
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Transplantation
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Transplantation, Homologous / adverse effects*
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Viral Load*
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Young Adult