Abstract
In September 2013, dengue virus (DENV) infection was diagnosed in a German traveller returning from Japan. DENV-specific IgM and IgG and DENV NS1 antigen were detected in the patient’s blood, as were DENV serotype 2-specific antibodies. Public health authorities should be aware that autochthonous transmission of this emerging virus may occur in Japan. Our findings also highlight the importance of taking a full travel history, even from travellers not returning from tropical countries, to assess potential infection risks of patients.
MeSH terms
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Antibodies, Viral / blood
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Antibodies, Viral / immunology
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Antigens, Viral / blood*
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Antigens, Viral / immunology
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Dengue / diagnosis*
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Dengue / immunology
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Dengue / transmission
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Dengue / virology
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Dengue Virus / genetics
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Dengue Virus / immunology
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Dengue Virus / isolation & purification*
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Enzyme-Linked Immunosorbent Assay
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Female
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Germany
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Humans
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Immunoglobulin G / blood
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Immunoglobulin G / immunology
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Immunoglobulin M / blood
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Immunoglobulin M / immunology
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Japan
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Middle Aged
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Reverse Transcriptase Polymerase Chain Reaction
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Travel*
Substances
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Antibodies, Viral
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Antigens, Viral
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Immunoglobulin G
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Immunoglobulin M