A case of EBV positive diffuse large B-cell lymphoma of the adolescent

Qilin Ao; Ying Wang; Sanpeng Xu; Ye Tian; Wei Huang

A case of EBV positive diffuse large B-cell lymphoma of the adolescent

Int J Clin Exp Med. 2014 Jan 15;7(1):307-11. eCollection 2014.

Authors

Qilin Ao¹, Ying Wang², Sanpeng Xu¹, Ye Tian², Wei Huang²

Affiliations

¹ Institute of Pathology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Da Dao, Wuhan 430030, P. R. China.
² Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology 1095 Jiefang Da Dao, Wuhan 430030, P. R. China.

PMID: 24482722
PMCID: PMC3902274

Abstract

EBV positive diffuse large B-cell lymphoma (DLBCL) can happen to the elderly, seldom to the young. The case of EBV positive DLBCL has rarely been reported in the adolescent. We report a rare case of EBV positive DLBCL in a 17-year-old man with normal immune state. He was diagnosed by morphology, immunohistochemistry, in situ hybridization for EBV, Flow cytometer, IG/TCR gene rearrangement and cytogenetic study. The occurrence of this case suggests that EBV-positive DLBCL can happen to adolescent patients with normal immune state and cytogenetic study takes an important role in the diagnosis of adolescent EBV-positive DLBCL.

Keywords: Diffuse large B-cell lymphoma; EBV; the adolescent.

Publication types

Case Reports