Ventilator-associated pneumonia due to extensive drug-resistant Acinetobacter baumannii: risk factors, clinical features, and outcomes

Am J Infect Control. 2014 Feb;42(2):206-8. doi: 10.1016/j.ajic.2013.09.003.

Abstract

Acinetobacter baumannii is characterized by a rapid development of resistance to the commonly used antimicrobial agents. We investigated the risk factors, clinical features, and outcomes in ventilator-associated pneumonia (VAP) caused by extensive drug-resistant Acinetobacter baumannii (XDRAB). Clinical parameters and overall in-hospital mortality rates were compared between the VAP with and without XDRAB infection groups. This study showed that VAP caused by XDRAB was not associated with in-hospital mortality. However, it was related to high Simplified Acute Physiology Score II scores and increasing durations of hospital stays.

Keywords: Acinetobacter baumannii; Outcome; SAPS II; Simplified Acute Physiology Score II; Ventilator-associated pneumonia.

MeSH terms

  • Acinetobacter Infections / epidemiology*
  • Acinetobacter Infections / microbiology
  • Acinetobacter Infections / mortality
  • Acinetobacter Infections / pathology*
  • Acinetobacter baumannii / drug effects*
  • Acinetobacter baumannii / isolation & purification
  • Adult
  • Aged
  • Cohort Studies
  • Drug Resistance, Multiple, Bacterial*
  • Female
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Pneumonia, Ventilator-Associated / epidemiology*
  • Pneumonia, Ventilator-Associated / microbiology
  • Pneumonia, Ventilator-Associated / mortality
  • Pneumonia, Ventilator-Associated / pathology*
  • Retrospective Studies
  • Risk Factors
  • Survival Analysis
  • Treatment Outcome