Morphology of layer V pyramidal neurons in the cat somatosensory cortex: an intracellular HRP study

Brain Res. 1987 Dec 29;437(2):369-74. doi: 10.1016/0006-8993(87)91654-4.

Abstract

Pyramidal tract (PT) or corticopontine neurons of the cat somatosensory cortex (SI) were identified with antidromic activation on stimulation of the bulbar pyramid or pontine nuclei (PN) and stained intracellularly with HRP after examining the electrophysiological properties. Comparison of the conduction velocity of the stem axons and the soma-dendritic morphology revealed that in the cat SI, there exists two types of layer V pyramidal neurons, i.e. one has smooth apical dendrites with larger soma (51.6 +/- 9.5 x 22.7 +/- 2.8 micron) and the other has richly spinous apical dendrites with smaller soma (34.0 +/- 8.8 x 15.3 +/- 3.3 micron). The former group responded antidromically at latencies shorter than 1 ms by PT stimulation or 1.5 ms by PN stimulation, respectively. These values were consistent with the borderline latencies between two similar groups of layer V pyramidal neurons in the motor (fast and slow PTNs) and parietal (aspiny and spiny layer V corticopontine neurons) cortices in the cat.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Afferent Pathways / cytology
  • Afferent Pathways / physiology
  • Animals
  • Axonal Transport
  • Cats
  • Electric Conductivity
  • Electric Stimulation
  • Horseradish Peroxidase
  • Neurons / cytology*
  • Neurons / physiology
  • Pyramidal Tracts / cytology*
  • Pyramidal Tracts / physiology
  • Somatosensory Cortex / cytology*
  • Somatosensory Cortex / physiology

Substances

  • Horseradish Peroxidase