ALK-rearranged adenosquamous lung cancer presenting as squamous cell carcinoma: a potential challenge to histologic type triaging of NSCLC biopsies for molecular studies

Clin Lung Cancer. 2014 May;15(3):e37-40. doi: 10.1016/j.cllc.2014.01.003. Epub 2014 Jan 18.
No abstract available

Keywords: ALK FISH; ALK rearrangement; Adenosquamous carcinoma; Molecular testing; Non–small-cell lung cancer.

Publication types

  • Case Reports

MeSH terms

  • Anaplastic Lymphoma Kinase
  • Biopsy / methods
  • Biopsy, Fine-Needle / methods
  • Carcinoma, Adenosquamous / diagnosis*
  • Carcinoma, Adenosquamous / genetics
  • Carcinoma, Adenosquamous / pathology
  • Carcinoma, Non-Small-Cell Lung / pathology
  • Carcinoma, Squamous Cell / diagnosis*
  • Carcinoma, Squamous Cell / pathology
  • Gene Rearrangement
  • Humans
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / genetics
  • Lung Neoplasms / pathology
  • Male
  • Middle Aged
  • Practice Guidelines as Topic
  • Receptor Protein-Tyrosine Kinases / genetics*

Substances

  • ALK protein, human
  • Anaplastic Lymphoma Kinase
  • Receptor Protein-Tyrosine Kinases