BRD4: a BET(ter) target for the treatment of AML?

Cell Cycle. 2014;13(5):689-90. doi: 10.4161/cc.27859. Epub 2014 Jan 21.
No abstract available

Keywords: AML; BRD4; JQ1; leukemic stem cells; targeted therapy.

Publication types

  • Editorial
  • Comment

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Azepines / pharmacology*
  • Female
  • Humans
  • Leukemia, Myeloid, Acute / metabolism*
  • Male
  • Molecular Targeted Therapy*
  • Neoplastic Stem Cells / drug effects*
  • Nuclear Proteins / antagonists & inhibitors*
  • Transcription Factors / antagonists & inhibitors*
  • Triazoles / pharmacology*

Substances

  • Antineoplastic Agents
  • Azepines
  • Nuclear Proteins
  • Transcription Factors
  • Triazoles