Identification of Babesia bigemina and Babesia bovis merozoite proteins with isolate- and species-common epitopes recognized by antibodies in bovine immune sera

Infect Immun. 1988 Jun;56(6):1658-60. doi: 10.1128/iai.56.6.1658-1660.1988.

Abstract

Immunoprecipitation of radiolabeled antigens with bovine antisera indicated that many Babesia bigemina and Babesia bovis merozoite proteins contain isolate-common epitopes, while at least 16 B. bigemina and 8 B. bovis proteins contain species-cross-reactive epitopes. One immunogenic, isolate-common, and species-specific candidate diagnostic protein from each species was identified.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antibodies, Bacterial*
  • Antigen-Antibody Reactions
  • Antigens, Protozoan / immunology
  • Antigens, Protozoan / isolation & purification*
  • Babesia / immunology*
  • Babesia / isolation & purification
  • Babesiosis / immunology*
  • Cattle
  • Cattle Diseases / immunology
  • Epitopes / immunology*
  • Species Specificity

Substances

  • Antibodies, Bacterial
  • Antigens, Protozoan
  • Epitopes