A new aromatic glycoside from Glehnia littoralis

Nat Prod Res. 2014;28(8):551-4. doi: 10.1080/14786419.2014.886206. Epub 2014 Feb 18.

Abstract

A new aromatic glycoside (1) was isolated from the roots of Glehnia littoralis Fr. Schmidtex Miq. Its structure was elucidated as vanillic acid 1-O-[β-D-apiofuranosyl-(1 → 6)-β-D-glucopyranoside] ester mainly by analysing the NMR and MS spectral data. In the in vitro assays, compound 1 displayed some TNF-α secretion inhibitory activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apiaceae / chemistry*
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Drugs, Chinese Herbal / pharmacology
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Roots / chemistry
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors
  • Tumor Necrosis Factor-alpha / metabolism
  • Vanillic Acid / analogs & derivatives*
  • Vanillic Acid / chemistry
  • Vanillic Acid / isolation & purification
  • Vanillic Acid / pharmacology

Substances

  • Drugs, Chinese Herbal
  • Glycosides
  • Tumor Necrosis Factor-alpha
  • vanillic acid 1-O-(beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside) ester
  • Vanillic Acid