Potential for use of the Seegene Anyplex MTB/NTM real-time detection assay in a regional reference laboratory

J Clin Microbiol. 2014 May;52(5):1708-10. doi: 10.1128/JCM.03585-13. Epub 2014 Feb 19.

Abstract

Requests for direct molecular diagnosis of mycobacterial disease are increasingly warranted. The Anyplex MTB/NTM assay demonstrates sensitivities, specificities, and positive and negative predictive values of 1.00, 0.96, 0.93, and 1.00 for Mycobacterium tuberculosis complex (MTBC) and 1.00, 0.97, 0.75, and 1.00 for nontuberculous mycobacteria (NTM) detection, respectively, making it a suitable screening test for mycobacterial detection.

MeSH terms

  • Mycobacterium Infections / diagnosis*
  • Mycobacterium Infections / microbiology
  • Mycobacterium Infections, Nontuberculous / diagnosis*
  • Mycobacterium Infections, Nontuberculous / microbiology
  • Mycobacterium tuberculosis / genetics
  • Nontuberculous Mycobacteria / genetics
  • Pathology, Molecular / methods*
  • Prospective Studies
  • Retrospective Studies
  • Sensitivity and Specificity
  • Tuberculosis / diagnosis*
  • Tuberculosis / microbiology