Hepatic cysts treated with percutaneous ethanol sclerotherapy: time to extend the indications to haemorrhagic cysts and polycystic liver disease

Eur Radiol. 2014 May;24(5):1030-8. doi: 10.1007/s00330-014-3117-x. Epub 2014 Feb 22.

Abstract

Objectives: To describe the long-term clinical and morphological outcome of symptomatic hepatic cysts treated with percutaneous ethanol sclerotherapy (PES).

Methods: From December 2003 to September 2011, all patients with hepatic cysts undergoing PES with a follow-up after 12 months were included. Evolution of the volume of the cysts and clinical and biological data were recorded. Features of the cyst were evaluated in each patient: simple, haemorrhagic or developed on underlying polycystic liver disease (PCLD).

Results: Fifty-eight cysts (median volume 666 mL) were treated in 57 patients (52 women, mean age 58 years (18-80)). Twenty-two patients (39 %) had simple hepatic cysts, 19 (33 %) had dominant cysts on PCLD and 20 had haemorrhagic cysts (34.5 %), including 4 with PCLD. After a mean 27.3 months of follow-up, the final median cystic volume was 13.5 mL (p < 0.0001), and the median reduction in cyst volume was 94 % (58-100 %). Treatment was satisfactory in 95 % of the patients (54/57) (symptoms disappeared in 45/57 (79 %), decreased in 9/57 (16 %)). There was no clinical or morphological difference between patients with PCLD, haemorrhagic cysts or simple cysts.

Conclusion: The clinical and morphological efficacy of a single session of PES is very high, regardless of the presence of intracystic haemorrhage or underlying PCLD.

Key points: • The clinical efficacy of percutaneous ethanol sclerotherapy is very high. • Haemorrhagic content should not be a contraindication for percutaneous sclerotherapy. • Dominant cysts on polycystic liver disease should be treated with PES. • Imaging follow-up should not be performed shortly after the procedure.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cysts / diagnostic imaging
  • Cysts / therapy*
  • Ethanol / therapeutic use*
  • Female
  • Hemorrhagic Disorders / diagnostic imaging
  • Hemorrhagic Disorders / therapy*
  • Humans
  • Liver Diseases / diagnostic imaging
  • Liver Diseases / therapy*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Multidetector Computed Tomography
  • Retrospective Studies
  • Sclerosing Solutions / therapeutic use*
  • Sclerotherapy / methods*
  • Treatment Outcome
  • Young Adult

Substances

  • Sclerosing Solutions
  • Ethanol

Supplementary concepts

  • Polycystic liver disease