Pertussis: a persistent cause of morbidity and mortality in young infants

Joseph B Cantey; Pablo J Sánchez; Judy Tran; Wendy Chung; Jane D Siegel

doi:10.1016/j.jpeds.2014.01.023

Pertussis: a persistent cause of morbidity and mortality in young infants

J Pediatr. 2014 Jun;164(6):1489-92.e1. doi: 10.1016/j.jpeds.2014.01.023. Epub 2014 Feb 22.

Authors

Joseph B Cantey¹, Pablo J Sánchez², Judy Tran³, Wendy Chung⁴, Jane D Siegel⁵

Affiliations

¹ Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX. Electronic address: [email protected].
² Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX.
³ Infection Control and Prevention, Children's Medical Center Dallas, Dallas, TX.
⁴ Dallas County Health and Human Services, Dallas, TX.
⁵ Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX; Infection Control and Prevention, Children's Medical Center Dallas, Dallas, TX.

PMID: 24565424
DOI: 10.1016/j.jpeds.2014.01.023

Abstract

In 2012, a pertussis outbreak in Dallas County resulted in the deaths of 4 children (3, unvaccinated; 2, <60 days of age). Despite recommendations that include immunization of women preferably during the third trimester of pregnancy or postpartum, household contacts ("cocooning"), and infants as early as 42 days of age, challenges in pertussis prevention remain.

MeSH terms

Academic Medical Centers
Child, Preschool
Diphtheria-Tetanus-acellular Pertussis Vaccines / administration & dosage*
Disease Outbreaks*
Female
Humans
Infant
Infant Mortality / trends*
Male
Pregnancy
Pregnancy Complications, Infectious / epidemiology
Pregnancy Complications, Infectious / prevention & control*
Pregnancy Trimester, Third
Risk Assessment
Survival Rate
Texas / epidemiology
Vaccination / methods
Whooping Cough / epidemiology*
Whooping Cough / prevention & control

Substances

Diphtheria-Tetanus-acellular Pertussis Vaccines