Abstract
Graft-versus-host-disease (GvHD) is despite improvement in transplantation medicine the major cause for morbidity and mortality after allogeneic stem cell transplantation. We describe a patient with chronic cutaneous GvHD who developed massive skin ulcerations after changing the immunosuppressive therapy to a mammalian target of rapamycin (mTOR)-inhibitor.
Publication types
-
Case Reports
-
English Abstract
MeSH terms
-
Everolimus
-
Graft vs Host Disease / drug therapy*
-
Graft vs Host Disease / etiology*
-
Humans
-
Immunosuppressive Agents / therapeutic use
-
Male
-
Middle Aged
-
Sirolimus / adverse effects
-
Sirolimus / analogs & derivatives*
-
Sirolimus / therapeutic use
-
Skin Ulcer / chemically induced*
-
Skin Ulcer / prevention & control
-
Stem Cell Transplantation / adverse effects*
-
Treatment Outcome
Substances
-
Immunosuppressive Agents
-
Everolimus
-
Sirolimus