Abstract
The NPY5 receptor binding and pharmacokinetic properties of a novel series of cis-1-oxo-heterocyclyl-4-amido-cyclohexane derivatives are described.
Keywords:
Neuropeptide Y5 receptor antagonist.
Copyright © 2014 Elsevier Ltd. All rights reserved.
MeSH terms
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Animals
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Cyclohexanes / chemical synthesis
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Cyclohexanes / chemistry*
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Cyclohexanes / pharmacokinetics
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Half-Life
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Humans
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Isomerism
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Mice
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Microsomes, Liver / metabolism
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Receptors, Neuropeptide Y / antagonists & inhibitors*
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Receptors, Neuropeptide Y / metabolism
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Structure-Activity Relationship
Substances
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Cyclohexanes
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Receptors, Neuropeptide Y
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neuropeptide Y5 receptor
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Cyclohexane