Association between the microarray-based CYP2C19 genotyping assay and the platelet function test in cardiovascular patients receiving clopidogrel

Int J Lab Hematol. 2014 Oct;36(5):e80-3. doi: 10.1111/ijlh.12194. Epub 2014 Mar 3.

Authors

J-L Choi¹, B-R Kim, J-E Kim, K-S Woo, K-H Kim, J-M Kim, M-H Kim, J-Y Han

Affiliation

¹ Departments of Laboratory Medicine, Dong-A University College of Medicine, Busan, Korea.

PMID: 24589079
DOI: 10.1111/ijlh.12194

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Acute Coronary Syndrome / ethnology
Acute Coronary Syndrome / genetics
Acute Coronary Syndrome / pathology
Acute Coronary Syndrome / therapy*
Adenosine Diphosphate / metabolism
Alleles
Asian People
Aspirin / therapeutic use*
Blood Platelets / drug effects
Blood Platelets / metabolism
Blood Platelets / pathology
Clopidogrel
Cytochrome P-450 CYP2C19 / genetics*
Cytochrome P-450 CYP2C19 / metabolism
Gene Expression
Genotype
Humans
Isoenzymes / genetics
Isoenzymes / metabolism
Microarray Analysis
Percutaneous Coronary Intervention
Platelet Aggregation Inhibitors / therapeutic use*
Polymorphism, Genetic*
Receptors, Purinergic P2Y12 / genetics
Receptors, Purinergic P2Y12 / metabolism
Ticlopidine / analogs & derivatives*
Ticlopidine / therapeutic use

Substances

Isoenzymes
P2RY12 protein, human
Platelet Aggregation Inhibitors
Receptors, Purinergic P2Y12
Adenosine Diphosphate
Clopidogrel
CYP2C19 protein, human
Cytochrome P-450 CYP2C19
Ticlopidine
Aspirin