Pattern-based strategy is an emerging field of interest for effective sensing applications. Seven different conjugated polymers from combinatorial synthesis were combined into a sensor array, and seven metal cations were selected as representative analytes. The response patterns for each cation were constructed by collecting the individual fluorescence responses from seven polymers in the array. Each ion owns a characteristic pattern. Some of them have similar modes of response with subtle differences, while some patterns are distinctively different. The family/period the metal cations belong to and the charges/electronic configurations they possess may account for such similarity/difference in the pattern.