Placental site trophoblastic tumor: Immunohistochemistry algorithm key to diagnosis and review of literature

John W Luiza; Sarah E Taylor; Faye F Gao; Robert P Edwards

doi:10.1016/j.gynor.2013.11.001

Placental site trophoblastic tumor: Immunohistochemistry algorithm key to diagnosis and review of literature

Gynecol Oncol Case Rep. 2013 Nov 21:7:13-5. doi: 10.1016/j.gynor.2013.11.001. eCollection 2014 Jan.

Authors

John W Luiza¹, Sarah E Taylor², Faye F Gao³, Robert P Edwards²

Affiliations

¹ University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
² Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh Medical Center, 300 Halket Street, Pittsburgh, PA 15213, USA.
³ Department of Pathology, Breast, and Gynecologic Pathology, Magee-Womens Hospital, University of Pittsburgh Medical Center, 300 Halket Street, Pittsburgh, PA 15213, USA.

Abstract

•Histologic morphology is frequently equivocal for PSTTs.•Histology combined with immunohistochemical staining was necessary to make the diagnosis.•PSTT confined to the uterus was successfully treated with surgery alone.

Keywords: Chemoresistant; Gestational trophoblastic neoplasm; Placental site trophoblastic tumor; hPL.