Radiofrequency ablation of intrahepatic cholangiocarcinoma: feasability, local tumor control, and long-term outcome

Selim R Butros; Anuradha Shenoy-Bhangle; Peter R Mueller; Ronald S Arellano

doi:10.1016/j.clinimag.2014.01.013

Radiofrequency ablation of intrahepatic cholangiocarcinoma: feasability, local tumor control, and long-term outcome

Clin Imaging. 2014 Jul-Aug;38(4):490-494. doi: 10.1016/j.clinimag.2014.01.013. Epub 2014 Feb 7.

Authors

Selim R Butros¹, Anuradha Shenoy-Bhangle², Peter R Mueller², Ronald S Arellano²

Affiliations

¹ Department of Radiology, Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., White 270, Boston, MA 02114, USA. Electronic address: [email protected].
² Department of Radiology, Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., White 270, Boston, MA 02114, USA.

PMID: 24637151
DOI: 10.1016/j.clinimag.2014.01.013

Abstract

A retrospective analysis of patients who underwent radiofrequency ablation (RFA) of intrahepatic cholangiocarcinoma (IHCC) was performed. Seven patients with 9 tumors underwent RFA. The mean tumor size was 2.4 cm (range=1.3-3.3 cm). RFA achieved technique effectiveness and local tumor control in 89% (8/9 tumors) of the patients respectively, with a mean overall survival of 38.5 months (range=12-69 months). To conclude, RFA was effective in achieving local tumor control and may offer a therapeutic option for patients with recurrent or primary IHCC.

Keywords: Cholangiocarcinoma; Liver tumor; Radiofrequency ablation; Thermal ablation.

MeSH terms

Adult
Aged
Aged, 80 and over
Bile Duct Neoplasms / mortality
Bile Duct Neoplasms / radiotherapy*
Bile Ducts, Intrahepatic
Catheter Ablation*
Cholangiocarcinoma / mortality
Cholangiocarcinoma / radiotherapy*
Cohort Studies
Female
Humans
Liver Neoplasms / mortality
Liver Neoplasms / radiotherapy*
Male
Middle Aged
Radiotherapy, Image-Guided
Retrospective Studies
Treatment Outcome