That's the "GIST" of it: use of adjuvant imatinib after resection of a primary GI stromal tumor

J Clin Oncol. 2014 May 20;32(15):1543-6. doi: 10.1200/JCO.2013.53.5971. Epub 2014 Mar 17.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / administration & dosage*
  • Benzamides / administration & dosage*
  • Biomarkers, Tumor / analysis
  • Biomarkers, Tumor / genetics
  • Biopsy
  • Chemotherapy, Adjuvant
  • Gastrectomy*
  • Gastrointestinal Stromal Tumors / chemistry
  • Gastrointestinal Stromal Tumors / drug therapy*
  • Gastrointestinal Stromal Tumors / genetics
  • Gastrointestinal Stromal Tumors / pathology
  • Gastrointestinal Stromal Tumors / surgery*
  • Humans
  • Imatinib Mesylate
  • Immunohistochemistry
  • Male
  • Middle Aged
  • Mitotic Index
  • Multimodal Imaging
  • Mutation
  • Neoplasm Staging
  • Patient Selection
  • Piperazines / administration & dosage*
  • Positron-Emission Tomography
  • Precision Medicine
  • Predictive Value of Tests
  • Protein Kinase Inhibitors / administration & dosage*
  • Proto-Oncogene Proteins B-raf / genetics
  • Proto-Oncogene Proteins c-kit / analysis
  • Proto-Oncogene Proteins c-kit / genetics
  • Pyrimidines / administration & dosage*
  • Receptor, Platelet-Derived Growth Factor alpha / genetics
  • Risk Factors
  • Stomach Neoplasms / chemistry
  • Stomach Neoplasms / drug therapy*
  • Stomach Neoplasms / genetics
  • Stomach Neoplasms / pathology
  • Stomach Neoplasms / surgery*
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Antineoplastic Agents
  • Benzamides
  • Biomarkers, Tumor
  • Piperazines
  • Protein Kinase Inhibitors
  • Pyrimidines
  • Imatinib Mesylate
  • Proto-Oncogene Proteins c-kit
  • Receptor, Platelet-Derived Growth Factor alpha
  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf