Aortic root enlargement in octogenarian patients results in less patient prosthesis mismatch

Ann Thorac Surg. 2014 May;97(5):1533-8. doi: 10.1016/j.athoracsur.2013.11.050. Epub 2014 Mar 19.

Abstract

Background: Aortic root enlargement has not been well studied as a modality to prevent patient prosthesis mismatch in octogenarian patients with a small aortic root.

Methods: We reviewed the records of 117 octogenarian patients who received surgical aortic valve replacement (AVR) between 1993 and 2010. From this group, 87 patients received a 19-mm AVR (small aortic valve, SAV group) and 30 received an aortic root enlargement and a 21-mm AVR (aortic root enlargement, ARE group).

Results: The median age of the patients was 84 years (range, 80 to 93) and there were 111 women (95%). Aortic cross-clamp time was 50 minutes (26 to 116) in the SAV group and 67 (26 to 136) in the ARE group (p=0.02). There were no differences in the operative morbidity or morality rates between the groups. Postoperative aortic valve area index was 0.77 cm2/m2 (0.25 to 1.47) in the SAV group and 1.06 (0.51 to 1.94) in the ARE group (p<0.001). Severe patient prosthesis mismatch occurred in 23 patients (32%) in the SAV group in comparison with 3 (12%) in the ARE group (p=0.04). There were no differences in the mid-term outcomes of New York Heart Association functional class (p=0.230) or survival between patients with or without mismatch (p=0.84).

Conclusions: Aortic root enlargement in octogenarian patients allows for insertion of larger aortic valve prostheses without any apparent increase in operative morbidity or mortality. The larger prostheses demonstrate better hemodynamic performance and less patient prosthesis mismatch, but no apparent functional or survival advantage.

Publication types

  • Comparative Study

MeSH terms

  • Aged, 80 and over
  • Aortic Valve / pathology
  • Aortic Valve / surgery*
  • Cohort Studies
  • Databases, Factual
  • Female
  • Follow-Up Studies
  • Geriatric Assessment
  • Heart Valve Prosthesis Implantation / methods*
  • Heart Valve Prosthesis Implantation / mortality
  • Heart Valve Prosthesis*
  • Humans
  • Male
  • Prosthesis Design
  • Prosthesis Fitting*
  • Retrospective Studies
  • Risk Factors
  • Survival Analysis
  • Tissue Expansion / methods*
  • Treatment Outcome
  • Vulnerable Populations