A turn-on fluorescent Fe(3+) sensor derived from an anthracene-bearing bisdiene macrocycle and its intracellular imaging application

Lin Qiu; Chengcheng Zhu; Huachao Chen; Ming Hu; Weijiang He; Zijian Guo

doi:10.1039/c3cc49482a

A turn-on fluorescent Fe(3+) sensor derived from an anthracene-bearing bisdiene macrocycle and its intracellular imaging application

Chem Commun (Camb). 2014 May 7;50(35):4631-4. doi: 10.1039/c3cc49482a.

Authors

Lin Qiu¹, Chengcheng Zhu, Huachao Chen, Ming Hu, Weijiang He, Zijian Guo

Affiliation

¹ State Key Laboratory of Coordination Chemistry, Coordination Chemistry Institute, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China. [email protected] [email protected].

PMID: 24668051
DOI: 10.1039/c3cc49482a

Abstract

Integrating N(2)-hydroxyethyldiethylenetriamine with anthracene gives a [2+2] macrocycle fluorescent sensor. This sensor displays an instant/reversible turn-on response specific to Fe(3+), which allows facile visualization of the Fe(3+)/Fe(2+) transition and intracellular Fe(3+) imaging.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anthracenes / chemistry*
Cations / analysis
Cell Line
Ferric Compounds / analysis*
Fluorescent Dyes / chemistry*
Humans
Hydrogen-Ion Concentration
Iron / analysis*
Iron Overload / diagnosis
Macrocyclic Compounds / chemistry
Optical Imaging*
Polyamines / chemistry*
Spectrometry, Fluorescence

Substances

Anthracenes
Cations
Ferric Compounds
Fluorescent Dyes
Macrocyclic Compounds
Polyamines
diethylenetriamine
Iron
anthracene