Proliferative retinopathy secondary to a branch vein occlusion developed in an otherwise healthy 24-year-old women who also had optic nerve drusen. Since the patient sustained a preretinal hemorrhage, quadrantic photocoagulation was applied to the nonperfused quadrant of the retina involved in the occlusion. This case illustrates that compression of a branch retinal vein is another potential complication of optic nerve drusen.