Hepatitis C virus replication compartment formation: mechanism and drug target

Gastroenterology. 2014 May;146(5):1164-7. doi: 10.1053/j.gastro.2014.03.017. Epub 2014 Mar 25.
No abstract available

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • 1-Phosphatidylinositol 4-Kinase / metabolism*
  • Antiviral Agents / pharmacology*
  • Cell Membrane / drug effects*
  • Cell Membrane / enzymology*
  • Cholesterol / metabolism*
  • Cyclophilin A / antagonists & inhibitors*
  • Cyclosporins / pharmacology*
  • Hepacivirus / drug effects*
  • Hepacivirus / enzymology*
  • Humans
  • Oxysterol Binding Proteins
  • RNA, Viral / biosynthesis*
  • Receptors, Steroid / metabolism*
  • Viral Nonstructural Proteins / metabolism*
  • Viral Proteins / metabolism*
  • Virus Replication / drug effects*

Substances

  • Antiviral Agents
  • Cyclosporins
  • NS2 protein, Hepatitis C virus
  • RNA, Viral
  • Receptors, Steroid
  • Viral Nonstructural Proteins
  • Viral Proteins
  • Oxysterol Binding Proteins
  • Cholesterol
  • 1-Phosphatidylinositol 4-Kinase
  • Cyclophilin A