Abstract
Fusarium is a saprophytic and opportunistic pathogen that can cause local tissue infection and life-threatening systemic infection. Systemic infection is rare and is observed primarily in immunocompromised patients. The early diagnosis is difficult, and the optimal treatment is unclear. However, the mortality is high. A 21-year-old man with aplastic anemia was treated with an allogeneic stem cell transplant. He developed fatal Fusarium solani infection. Fusarium species may be overlooked pathogenic fungi in immunocompromised patients, especially bone marrow transplant recipients.
MeSH terms
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Anemia, Aplastic / diagnosis
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Anemia, Aplastic / surgery*
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Antifungal Agents / therapeutic use
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Fatal Outcome
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Fusariosis / diagnosis
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Fusariosis / drug therapy
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Fusariosis / microbiology*
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Fusarium / isolation & purification*
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Humans
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Immunocompromised Host
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Immunosuppressive Agents / adverse effects
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Male
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Ophthalmoscopy
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Opportunistic Infections / diagnosis
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Opportunistic Infections / drug therapy
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Opportunistic Infections / microbiology*
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Stem Cell Transplantation / adverse effects*
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Time Factors
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Tomography, X-Ray Computed
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Transplantation, Homologous
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Treatment Outcome
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Young Adult
Substances
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Antifungal Agents
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Immunosuppressive Agents