Emerging frontiers in detection and control of bacterial biofilms

Curr Opin Biotechnol. 2014 Apr:26:1-6. doi: 10.1016/j.copbio.2013.08.002. Epub 2013 Aug 31.

Abstract

Bacteria form surface-attached biofilm communities in nature. In contrast to free-living cells, bacterial cells within biofilms resist sanitizers and antimicrobials. While building biofilms, cells physiologically adapt to sustain the otherwise lethal impacts of a variety of environmental stress conditions. In this development, the production and embedding of cells in extracellular polymeric substances plays a key role. Biofilm bacteria can cause a range of problems to food processing including reduced heat-cold transfer, clogging water pipelines, food spoilage and they may cause infections among consumers. Recent biofilm investigations with the aim of potential control approaches include a combination of bacterial genetics, systems biology, materials and mechanic engineering and chemical biology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacteria / drug effects
  • Bacteria / genetics
  • Bacteria / growth & development
  • Bacteria / isolation & purification*
  • Biofilms / drug effects
  • Biofilms / growth & development*
  • Chemical Engineering
  • Food Handling / methods
  • Food Microbiology*
  • Humans
  • Materials Testing
  • Systems Biology