Outbreak of AmpC β-lactamase-hyper-producing Enterobacter cloacae in a neonatal intensive care unit in a French teaching hospital

Am J Infect Control. 2014 Apr;42(4):456-8. doi: 10.1016/j.ajic.2013.11.005.

Abstract

We report the investigation of an outbreak of colonization by a wild-type Enterobacter cloacae and its AmpC-hyper-producing derivative E cloacae in a neonatal intensive care unit. E cloacae hyper-producing AmpC β-lactamase isolates were found from neonate specimens and from environmental samples. All the isolates belonged to the same clone.

Keywords: Breast-feeding; Cross transmission; Pulsed-field electrophoresis.

Publication types

  • Case Reports

MeSH terms

  • Bacterial Proteins / metabolism*
  • Cross Infection / epidemiology
  • Cross Infection / microbiology*
  • Disease Outbreaks*
  • Electrophoresis, Gel, Pulsed-Field
  • Enterobacter cloacae / classification
  • Enterobacter cloacae / enzymology*
  • Enterobacter cloacae / genetics
  • Enterobacter cloacae / isolation & purification
  • Enterobacteriaceae Infections / epidemiology
  • Enterobacteriaceae Infections / microbiology*
  • Environmental Microbiology
  • Female
  • France / epidemiology
  • Genotype
  • Hospitals, Teaching
  • Humans
  • Infant, Newborn
  • Intensive Care, Neonatal*
  • Male
  • Molecular Epidemiology
  • Molecular Typing
  • beta-Lactamases / metabolism*

Substances

  • Bacterial Proteins
  • AmpC beta-lactamases
  • beta-Lactamases