Superparamagnetic-oil-filled nanocapsules of a ternary graft copolymer

Langmuir. 2014 Apr 15;30(14):3996-4004. doi: 10.1021/la500415u. Epub 2014 Mar 31.

Abstract

Stearic and oleic acid-coated Fe3O4 nanoparticles were dispersed in decahydronaphthalene (DN). This oil phase was dispersed in water using ternary graft copolymer poly(glycidyl methacrylate)-graft-[polystyrene-ran-(methoxy polyethylene glycol)-ran-poly(2-cinnamoyloxyethyl methacrylate)] or PGMA-g-(PS-r-MPEG-r-PCEMA) to yield capsules. The walls of these capsules were composed of PCEMA chains that were soluble in neither water nor DN, and the DN-soluble PS chains stretched into the droplet phase and the water-soluble MPEG chains extended into the aqueous phase. Structurally stable capsules were prepared by photolyzing the capsules with UV light to cross-link the PCEMA layer. Both the magnetite particles and the magnetite-containing capsules were superparamagnetic. The sizes of the capsules increased as they were loaded with more magnetite nanoparticles, reaching a maximal loading of ~0.5 mg of ligated magnetite nanoparticles per mg of copolymer. But the radii of the capsules were always <100 nm. Thus, a novel nanomaterial--superparamagnetic-oil-filled polymer nanocapsules--was prepared. The more heavily loaded capsules were readily captured by a magnet and could be redispersed via shaking. Although the cross-linked capsules survived this capturing and redispersing treatment many times, the un-cross-linked capsules ruptured after four cycles. These results suggest the potential to tailor-make capsules with tunable wall stability for magnetically controlled release applications.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Magnetite Nanoparticles / chemistry*
  • Molecular Structure
  • Naphthalenes / chemistry
  • Oils / chemistry*
  • Oleic Acid / chemistry
  • Particle Size
  • Polymers / chemical synthesis
  • Polymers / chemistry*
  • Stearic Acids / chemistry
  • Surface Properties

Substances

  • Magnetite Nanoparticles
  • Naphthalenes
  • Oils
  • Polymers
  • Stearic Acids
  • Oleic Acid
  • stearic acid
  • decalin