Virus templated gold nanocube chain for SERS nanoprobe

Small. 2014 Aug 13;10(15):3007-11. doi: 10.1002/smll.201400527. Epub 2014 Apr 3.

Abstract

A M13 virus based SERS nanoprobe is presented. Gold nanocubes closely aligned into chains along the length of the virus intensify Raman signals of various reporter molecules serving as specific labels. An antibody is expressed at one end to detect the analyte. This new SERS nanoprobe holds promise for infinitesimal and multiplexed detection of any antigen.

Keywords: M13 virus; gold nanoparticle assembly; nanoprobe; surface-enhanced Raman scattering.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteriophage M13 / chemistry
  • Bacteriophage M13 / ultrastructure*
  • Equipment Design
  • Equipment Failure Analysis
  • Gold / chemistry*
  • Immunoassay / instrumentation*
  • Metal Nanoparticles / chemistry
  • Metal Nanoparticles / ultrastructure*
  • Molecular Imprinting / methods*
  • Spectrum Analysis, Raman / instrumentation*
  • Surface Plasmon Resonance / instrumentation
  • Surface Properties

Substances

  • Gold