Intermolecular domino reaction of two aryl iodides involving two C-H functionalizations

Marcel Sickert; Harald Weinstabl; Brendan Peters; Xiao Hou; Mark Lautens

doi:10.1002/anie.201400807

Intermolecular domino reaction of two aryl iodides involving two C-H functionalizations

Angew Chem Int Ed Engl. 2014 May 12;53(20):5147-51. doi: 10.1002/anie.201400807. Epub 2014 Apr 3.

Authors

Marcel Sickert¹, Harald Weinstabl, Brendan Peters, Xiao Hou, Mark Lautens

Affiliation

¹ Department of Chemistry, University of Toronto, 80 St. George St. Toronto, Ontario, M5S 3H6 (Canada) http://www.chem.utoronto.ca/staff/ML/index.php.

PMID: 24700740
DOI: 10.1002/anie.201400807

Abstract

A palladium-catalyzed intermolecular cross-coupling of two aryl iodides is reported, giving polycyclic ring systems with a high level of convergence and efficiency.

Keywords: CH activation; carbopalladation; domino reactions; fused-ring systems; palladium.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Dimerization
Iodides / chemistry*

Substances

Iodides